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Titans vs. Jaguars Same Game Parlay Picks – NFL Week 17BOONE, N.C. (AP) — South Carolina offensive coordinator Dowell Loggains has been hired as head coach at Appalachian State and will receive a five-year contract, athletic director Doug Gillin announced Saturday. The 44-year-old Loggains replaces Shawn Clark, who was fired Monday after the Mountaineers finished 5-6 for their first losing season since 2013. Loggains was South Carolina's offensive coordinator for two seasons and an assistant at Arkansas, his alma mater, for two seasons before that. He spent 16 years in the NFL as offensive coordinator and quarterbacks coach for Tennessee, Cleveland, Chicago, Miami and the New York Jets. “He brings experience as a leader and play-caller at the highest levels of professional and college football," Gillin said. "He is a great recruiter and believes strongly in building relationships. He is aligned with our core values of academic integrity, competitive excellence, social responsibility and world-class experience. This is a great day for App State.” Loggains' offense at South Carolina featured LaNorris Sellers, one of the nation's top dual-threat quarterbacks, and running back Raheim “Rocket” Sanders. Sellers and Sanders led the Southeastern Conference's third-ranked rushing offense. Story continues below video Loggains spent the 2021 and 2022 seasons as Arkansas' tight ends coach, and he worked with Sam Darnold, Jay Cutler, Mitchell Trubisky, Brian Hoyer and Vince Young during his time in the NFL. The Mountaineers, the preseason favorites in the Sun Belt Conference's East Division, tied for fifth with a 3-5 record in league play. App State was 40-24 under Clark, but the Mountaineers have failed to reach a bowl game two of the past three seasons. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football

The standard Lorem Ipsum passage, used since the 1500s "Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum." Section 1.10.32 of "de Finibus Bonorum et Malorum", written by Cicero in 45 BC "Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur? Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur?" Thanks for your interest in Kalkine Media's content! To continue reading, please log in to your account or create your free account with us.TEL AVIV, Israel (AP) — Israeli Prime Minister Benjamin Netanyahu underwent successful surgery Sunday to have his prostate removed, hospital officials said, a procedure that came as he manages multiple crises including the war in Gaza and his trial for alleged corruption . Netanyahu, who has had a series of health issues in recent years, has gone to great lengths to bolster a public image of himself as a healthy, energetic leader. During his trial this month, he boasted about working 18-hour days, accompanied by a cigar. But as Israel's longest-serving leader, such a grueling workload over a total of 17 years in power could take a toll on his well-being. Netanyahu, 75, is among older world leaders including U.S. President Joe Biden, 82 , President-elect Donald Trump, 78 , Brazil's President Luiz Inácio Lula da Silva , 79, and Pope Francis , 88, who have come under scrutiny for their age and health issues. Netanyahu's latest condition is common in older men, but the procedure has had some fallout. The judges overseeing his trial accepted a request from his lawyer on Sunday to call off three days of testimony scheduled this week. The lawyer, Amit Hadad, had argued that Netanyahu would be fully sedated for the procedure and hospitalized for “a number of days.” Dr. Ofer Gofrit, head of the urology department at Jerusalem's Hadassah Medical Center, said in a video statement late Sunday that the procedure had gone well and “there was no fear” of cancer or malignancy. “We only hope for the best,” he said. In a statement, Netanyahu thanked his doctors. His office said he was "fully alert" and was taken to an underground recovery unit fortified against potential missile attacks. Netanyahu was expected to remain in the hospital for several days of observation. Justice Minister Yariv Levin, a close ally, served as acting prime minister during the operation. With so much at stake, Netanyahu’s health in wartime is a concern for both Israelis and the wider world. A turbulent time in the region As Israel’s leader, Netanyahu is at the center of major global events that are shifting the Middle East . With the dizzying pace of the past 14 months, being incapacitated for even a few hours can be risky. Netanyahu will be in the hospital at a time when international mediators are pushing Israel and Hamas to reach a ceasefire in Gaza and as fighting between Israel and Yemen’s Iran-backed Houthi rebels intensifies . Prostate issues are common and in many cases easily treatable. Still, the procedure puts a dent in Netanyahu’s image of vigor at a time when he would want to project strength more than ever, both to an Israeli audience navigating constant threats as well as to Israel’s enemies looking to expose its weaknesses. Previous health issues, including a heart condition Netanyahu insists he is in excellent health. His office releases footage of him touring war zones in full protective gear flanked by military officers, or meeting with defense officials on windswept hilltops in youthful dark shades and puffer jackets. But that image was shattered last year when Netanyahu’s doctors revealed that he had a heart condition , a problem that he had apparently long known about but concealed from the public. A week after a fainting spell, Netanyahu was fitted with a pacemaker to control his heartbeat. Only then did staff at the Sheba Medical Center reveal that Netanyahu has for years experienced a condition that can cause irregular heartbeats. The revelation came as Netanyahu was dealing with massive anti-government protests. The news about a chronic heart problem stoked further anger and distrust during extreme political polarization in Israel. Last year, Netanyahu was rushed to the hospital for what doctors said likely was dehydration . He stayed overnight, prompting his weekly Cabinet meeting to be delayed. Earlier this year, Netanyahu underwent hernia surgery , during which he was under full anesthesia and unconscious. Levin served as acting prime minister during the operation. Recovery can be quick According to Netanyahu’s office, the Israeli leader was diagnosed with a urinary tract infection on Wednesday stemming from a benign enlargement of his prostate. The infection was treated successfully with antibiotics, but doctors said the surgery was needed in any case. Complications from prostate enlargement are common in men in their 70s and 80s, Dr. Shay Golan, head of the oncology urology service at Israel’s Rabin Medical Center, told Israeli Army Radio. Golan spoke in general terms and was not involved in Netanyahu’s care or treatment. He said an enlarged prostate can block proper emptying of the bladder, leading to a build-up of urine that can lead to an infection or other complications. After medicinal treatment, doctors can recommend a procedure to remove the prostate to prevent future blockages, Golan said. In Netanyahu’s case, because the prostate is not cancerous, Golan said doctors were likely performing an endoscopic surgery, carried out by inserting small instruments into a body cavity, rather than making surgical cuts in the abdomen to reach the prostate. The procedure lasts about an hour, Golan said, and recovery is quick. He said that aside from catheter use for one to three days after the procedure, patients can return to normal activity without significant limitations. AP correspondent Isaac Scharf contributed reporting.Golden at-bat idea brings critics to the plate: ‘Absolutely stupid and ridiculous’

President-elect Donald Trump on Wednesday announced former Sen. Kelly Loeffler as his pick to lead the Small Business Administration. “Kelly will bring her experience in business and Washington to reduce red tape, and unleash opportunity for our Small Businesses to grow, innovate, and thrive. She will focus on ensuring that SBA is accountable to Taxpayers by cracking down on waste, fraud, and regulatory overreach,” Trump posted on Truth Social, also noting that she’s co-chairing his inauguration. There had been several discussions between Loeffler and the transition team regarding the role of Agriculture secretary, and CNN reported last month that Trump had been poised to offer her the position. But Trump held off from announcing his Agriculture pick as he issued a slew of others late last month, then eventually offered the role to Brooke Rollins . Loeffler, who briefly represented Georgia in the Senate, had fundraised for Trump during the 2024 race and raised several million dollars for his campaign over the summer when she hosted a debate watch party with Republican National Committee Chair Michael Whatley. Several of Trump’s other Cabinet picks — including Sen. Marco Rubio and Rep. Elise Stefanik — were at that party. Loeffler was among the wealthiest lawmakers during her short time in Congress. Her husband, Jeffrey Sprecher, is the CEO of the Intercontinental Exchange, which owns the New York Stock Exchange. When running for election in 2020, she announced she and her husband were divesting from individual stocks amid sharp criticism over trades she and other lawmakers made ahead of the market downturn caused by the coronavirus. Appointed to the Senate by Georgia Gov. Brian Kemp over the wishes of Trump, Loeffler lost her seat in a 2021 runoff to Democratic now-Sen. Raphael Warnock. Loeffler was a staunch Trump ally in Congress, saying prior to the violence on January 6, 2021, that she planned to vote against certifying her state’s electoral results in support of Trump’s broader effort to upend Joe Biden’s 2020 election victory. After the US Capitol attack, Loeffler backed off her objection, saying on the Senate floor: “When I arrived in Washington this morning, I fully intended to object to the certification of the electoral votes. However, the events that have transpired today have forced me to reconsider, and I cannot now in good conscience object to the certification of these electors.” In the same speech, Loeffler condemned the violence at the Capitol, calling it “abhorrent.” Loeffler was among the witnesses who appeared before the grand jury as part of Trump’s 2020 election subversion criminal case in Georgia. Before joining the Senate, Loeffler served as an executive at a financial services firm in Atlanta. She was also a co-owner of the WNBA’s Atlanta Dream. Loeffler would need to be confirmed by the Senate to lead the Small Business Administration. Linda McMahon, a major Republican donor and Trump’s pick to be the next education secretary , served as the administrator of the agency during Trump’s first term. She resigned in 2019 to become the chair of America First Action, a pro-Trump super PAC. This story has been updated with additional details.

Ohio Senate passes bill to preserve intent of Alford plea

According to The Athletic’s Jovan Buha, the Los Angeles Lakers remain steadfast in their trade evaluation process, adhering to their established criteria. “I’ve heard the Lakers have been patient with the trade approach relatively and it’s been more of them waiting toward that February 6 date,” Buha said at the 1:05:45 mark in the newest episode of his Buha’s Block podcast. “If the right deal comes up sooner they will make it but it’s seemingly been more than kind of waiting this out until mid-to-late January on the early side.” Lakers are in no hurry to make much-needed moves. Prior to the start of the 2024-25 season, Lakers general manager Rob Pelinka indicated the team’s openness to exploring potential blockbuster trades. However, he emphasized the need for thorough evaluation, setting a timeline of approximately 30 games to assess the current roster’s strengths and weaknesses. The Lakers apparently came across the right deal. On its face, Pelinka’s deal sending D’Angelo Russell, Maxwell Lewis and three second-round picks to the Brooklyn Nets for Dorian Finney-Smith and Shake Milton, addresses a need for non-Lebron James/Anthony Davis offense and sturdiness on defense, as well as alleviating Russell’s high expense. But the Lakers’ top needs still need to be addressed, so Buha’s assertion remains relevant. The Lakers have been strongly and consistently linked to Washington Wizards center Jonas Valanciunas, as well as other big men, such as Walker Kessler and Robert Williams III. They have also expressed interest in several backcourt players, most recently the Sacramento Kings, De’Aaron Fox, as well as, Kyle Kuzma of the Wizards and the Utah Jazz’s Collin Sexton. The Lakers’ recent strategic changes have fueled a resurgence resulting in five wins over the last six games. That along with the addition of Finney-Smith allows Pelinka more time to find the right fit to push its competitive edge to its highest level. So at the very least this move buys them more time. This article first appeared on LAFB Network and was syndicated with permission.

Rett syndrome is a rare and complex neurodevelopmental disorder that affects approximately 6,000 to 9,000 patients in the U.S.1,2 It typically presents in children ages 6 to 18 months, with symptoms such as stereotypic hand movements, like wringing and clapping, and loss of acquired speech and motor skills.3,4 Diagnosis can take two to four years after symptoms first appear, with many cases confirmed around age 3.5 Most individuals with Rett syndrome live into adulthood, requiring continuous care, often provided by family members.2,6,7 This responsibility can be emotionally, physically and financially challenging for parents.7 “Rett syndrome presents an array of debilitating and often unpredictable features over the course of a patient’s life,” said Alan Percy, M.D., professor of pediatrics, neurology, neurobiology, genetics and psychology at the University of Alabama at Birmingham. “Patients with Rett syndrome and their families may face many challenges as this disorder becomes part of their daily routine. While no cure is available, a combination of supportive therapies and treatment with DAYBUETM (trofinetide), the first and only FDA-approved drug for Rett syndrome in adults and pediatric patients 2 years of age and older, can lead to meaningful improvements for patients, offering hope to families.” The following stories, shared by parents reflecting on their children’s experience with DAYBUE and other supportive therapies, highlight these families’ resilience and optimism. The families featured are paid Acadia consultants and were compensated for sharing their stories. Ellie’s Story Ellie is a 15-year-old girl from a family of four. Her mother, Heidi; father, Rob; and younger brother, Rhys, all adore her, and those who know her can’t help but feel the same. “Ellie’s kind of shy when you first meet her, and it can take some time to warm up, but when she does connect with you, you’re hooked,” Heidi said. The family spends lots of time together, taking ski trips up the Colorado mountains. Although Ellie’s parents started her on speech and yoga therapy at age 2 to address her developmental symptoms, she wasn’t diagnosed with Rett syndrome until she was 7 years old. Ellie displayed some of the common symptoms seen in children with Rett. She couldn’t communicate. Repetitive hand movements prevented her from grasping objects. She would have off days, acting out in emotional outbursts. Since her diagnosis, Ellie’s treatment has expanded to physical, speech, occupational and swim therapy. Ellie also started taking the medication DAYBUE. With therapy and medication, Heidi has seen an impactful difference in Ellie’s symptoms as she watches her daughter’s personality and unique interests shine through. According to Heidi, some of the changes “come in these small, beautiful moments we wouldn’t always pay attention to.” On one family trip, Ellie exclaimed, “Fun!” after a day of adaptive skiing. “It was a big deal!” Heidi said of that moment. This may seem like a small victory, but to Ellie’s family, it’s a big and hopeful leap forward. “Ellie is just like any other teen,” said Heidi. “She loves music, especially boy bands, and gives a great teenage eye roll.” Olivia’s Story Olivia is a bubbly 5-year-old who loves to smile. From an active family of four, Olivia is partial to the outdoors, particularly the backyard swimming pool, her happy place. Besides the pool, Olivia loves going to school. “Some days when she gets off the bus, she cries because she knows her day is over,” said her father, Jeff. Olivia also loves playing with other children. Her favorite playmate is her older brother. “Nick plays with her and shows her things,” Jeff said. “He likes having her as an audience.” Olivia was a talkative child. Then, at around 15 to 18 months old, she stopped speaking. “She was saying lots of words — simple words that kids start off with. Then those words suddenly went away,” Jeff said. She had low muscle tone and stopped climbing on furniture. She had difficulty grasping objects. Olivia’s mother, Peggy, studied early childhood development and saw these as red flags. Peggy and Jeff expressed their concerns to a pediatrician, who ordered an MRI. The results were normal. Still, the pediatrician thought it best to enroll Olivia in early-development classes, including physical, speech and occupational therapy. The results were promising. Olivia started walking. She was vocal and used sounds to convey her needs. In December 2021, about a year and a half later, Olivia was sent to the emergency room for heavy breathing. After assessing Olivia’s developmental history, the doctor ordered a genetic test. At 21⁄2 years old, Olivia was diagnosed with Rett syndrome. Jeff and his wife began educating themselves about the condition, consulting advocacy groups and continuing with Olivia’s speech, occupational and physical therapy. In July 2023, a neurologist prescribed DAYBUE, which she takes in combination with her supportive therapies. The family has seen noticeable differences in Olivia. “Since we started Olivia on this combined treatment plan, we’ve seen it’s really helped to manage her symptoms,” Jeff said. “Olivia loves being social and engaged in the world around her. It means everything to us that we continue to find ways for her to participate in our family activities and also support her to pursue her interests, despite her Rett syndrome symptoms.” These victories, no matter how small, bring great hope to Olivia’s family. Ellie and Olivia did experience some side effects when taking DAYBUE. See below for Important Safety Information related to diarrhea, vomiting, weight loss and other possible side effects of DAYBUE. Ellie’s and Olivia’s stories bring hope to families caring for children with Rett syndrome. The experiences of Ellie, Olivia and their families may not be the same as yours. Because everyone with Rett syndrome is unique — with a unique set of symptoms — the response to DAYBUE may be different for each individual. To learn more, visit DAYBUE.com/caregiver-stories . All photos provided by Acadia. About DAYBUE What is DAYBUE? DAYBUE is a prescription medicine used to treat Rett syndrome in adults and children 2 years of age and older. It is not known if DAYBUE is safe and effective in children under 2 years of age. DAYBUE Important Safety Information What are the possible side effects of DAYBUE? Diarrhea : Diarrhea is a common side effect of DAYBUE that can sometimes be severe. Diarrhea may cause you to lose too much water from your body (dehydration). Before starting treatment with DAYBUE, stop taking laxatives. Tell your healthcare provider if you have diarrhea while taking DAYBUE. Your healthcare provider may ask you to increase the amount you drink or take antidiarrheal medicine as needed. Vomiting: Vomiting is a common side effect of DAYBUE. Sometimes vomit can get into your lungs (aspiration), which could cause an infection (aspiration pneumonia). Tell your healthcare provider if you have severe vomiting or if vomiting happens often. Weight loss : DAYBUE can cause weight loss. Tell your healthcare provider if you notice you are losing weight at any time during treatment with DAYBUE. The most common side effects of DAYBUE were diarrhea and vomiting. Other side effects include fever, seizure, anxiety, decreased appetite, tiredness, and the common cold. These are not all the possible side effects of DAYBUE. Tell your healthcare provider if you have any side effects that bother you or do not go away. What should I tell my healthcare provider before taking DAYBUE? Before taking DAYBUE, tell your healthcare provider about all of your medical conditions, including if you: have kidney problems. are pregnant or plan to become pregnant. It is not known if DAYBUE will harm your unborn baby. are breastfeeding or plan to breastfeed. It is not known if DAYBUE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking DAYBUE. Tell your healthcare provider about all of the medicines you take , including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking DAYBUE with certain medicines may affect how the other medicines work and can cause serious side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088 . You can also call Acadia Pharmaceuticals Inc. at 1-844-4ACADIA (1-844-422-2342). DAYBUE is available as an oral solution (200mg/mL). The risk information provided here is not comprehensive. To learn more, talk with your healthcare provider and read the full Prescribing Information , including Patient Information, also available at DAYBUE.com . *** 1. Acadia Pharmaceuticals Inc. Data on file. RTT US Prevalence. March 2022. 2. Fu C, Armstrong D, Marsh E, et al. Consensus guidelines on managing Rett syndrome across the lifespan. BMJ Paediatrics Open. 2020; 4: 1-14. 3. Kyle SM, Vashi N, Justice MJ. Rett syndrome: a neurological disorder with metabolic components. Open Biol. 2018; 8:170216. 4. Neul JL, Kaufmann WE, Glaze DG, et al. Rett syndrome: revised diagnostic criteria and nomenclature. Ann Neurol . 2010;68(6):944-950. 5. Tarquinio DC, Hou W, Neul JL, et al. Age of diagnosis in Rett syndrome: patterns of recognition among diagnosticians and risk factors for late diagnosis. Pediatric Neurology . 2015; 52: 585-591. 6. Daniel C, Tarquinio DO, Hou W, et al. The changing face of survival in Rett syndrome and MECP2-related disorders. Pediatr Neurol . 2015; 53(5): 402-411. 7. Palacios-Cena D, Famoso-Perez P, Salom-Moreno J, et al. “Living an obstacle course”: a qualitative study examining the experiences of caregivers of children with Rett syndrome. In. J. Environ. Res. Public Health . 2018; 16 (41): 1-10. DAY-US-0331 11/24 Related

Jimmy Carter had the longest post-presidency of anyone to hold the office, and one of the most active. Here is a look back at his life. 1924 — Jimmy Carter was born on Oct. 1 to Earl and Lillian Carter in the small town of Plains, Georgia. 1928 — Earl Carter bought a 350-acre farm 3 miles from Plains in the tiny community of Archery. The Carter family lived in a house on the farm without running water or electricity. 1941 — He graduated from Plains High School and enrolled at Georgia Southwestern College in Americus. 1942 — He transferred to Georgia Institute of Technology in Atlanta. 1943 — Carter’s boyhood dream of being in the Navy becomes a reality as he is appointed to the U.S. Naval Academy in Annapolis, Maryland. 1946 — He received his naval commission and on July 7 married Rosalynn Smith of Plains. They moved to Norfolk, Virginia. 1946-1952 — Carter’s three sons are born, Jack in 1947, Chip in 1950 and Jeff in 1952. 1962-66 — Carter is elected to the Georgia State Senate and serves two terms. 1953 — Carter’s father died and he cut his naval career short to save the family farm. Due to a limited income, Jimmy, Rosalynn and their three sons moved into Public Housing Apartment 9A in Plains. 1966 — He ran for governor, but lost. 1967 — Jimmy and Rosalynn Carter’s fourth child, Amy, is born. 1971 — He ran for governor again and won the election, becoming Georgia’s 76th governor on Jan. 12. 1974 — Carter announced his candidacy for president. 1976 — Carter was elected 39th president on Nov. 2, narrowly defeating incumbent Gerald Ford. 1978 — U.S. and the Peoples’ Republic of China establish full diplomatic relations. President Carter negotiates and mediates an accord between Egypt and Israel at Camp David. 1979 — The Department of Education is formed. Iranian radicals overrun the U.S. Embassy and seize American hostages. The Strategic Arms Limitations Treaty is signed. 1980 — On March 21, Carter announces that the U.S. will boycott the Olympic Games scheduled in Moscow. A rescue attempt to get American hostages out of Iran is unsuccessful. Carter was defeated in his bid for a second term as president by Ronald Reagan in November. 1981 — President Carter continues to negotiate the release of the American hostages in Iran. Minutes before his term as president is over, the hostages are released. 1982 — Carter became a distinguished professor at Emory University in Atlanta, and founded The Carter Center. The nonpartisan and nonprofit center addresses national and international issues of public policy. 1984 — Jimmy and Rosalynn Carter volunteer one week a year for Habitat for Humanity, a nonprofit organization that helps needy people in the United States and in other countries renovate and build homes, until 2020. He also taught Sunday school in the Maranatha Baptist Church of Plains from the mid-’80s until 2020. 2002 — Awarded the Nobel Peace Prize. 2015 — Carter announced in August he had been diagnosed with melanoma that spread to his brain. 2016 — He said in March that he no longer needed cancer treatment. 2024 — Carter dies at 100 years old. Sources: Cartercenter.org, Plains Historical Preservation Trust, The Associated Press; The Brookings Institution; U.S. Navy; WhiteHouse.gov, GallupNo. 22 Syracuse looking for 10 wins in 1st year under Fran Brown against depleted Washington State

Police forces report sharp rise in religious hate crimes across UKSam’s Club: Bennett, Reinhart on Team Canada for 4 Nations Face-Off

US stocks surge to records, shrugging off upheaval in South Korea, France

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